Tuesday, April 22, 2008

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Friday, April 11, 2008

A "Healthy" Move That Can Hurt You

When celebs such as Beyonce and Gwyneth rave about a detox diet, it's easy to think they're onto something. Who wouldn't want to lose 5 pounds in three days? But the truth is, these plans aren't good for you and could even make you sick. SELF went to top women's-health experts to bust the biggest myths.

THE MYTH. You'll clear disease-causing toxins.

THE FACTS. "The body isn't a cesspool that needs to be drained," says David Robbins, M.D., assistant professor of medicine at Beth Israel Medical Center in New York City. Your intestines were made to hold and eliminate toxins. As long as you eat a complete diet with plenty of fiber, they do their job fine.

THE MYTH. You'll shed pounds quickly.

THE FACTS. Some diets ban solid food, but "weight you lose on a liquid diet is mainly water," says Dawn Jackson Blatner, R.D., a spokeswoman in Chicago for the American Dietetic Association. "When you reintroduce solid foods, you'll gain it back." SELF's Jump Start Diet on page 77 is a better plan.

THE MYTH. You'll feel more energized.

THE FACTS. If your diet is high in refined carbs, you will get a temporary lift when you cut them out, Jackson Blatner says. But that's because you're eating healthier and avoiding sugar highs and lows. Eliminating food groups, especially protein, or fasting will tucker you out.

Mild cognitive impairment and Alzheimer’s

New technologies help determine whether cognitive impairment will lead to Alzheimer’s, from the Harvard Mental Health Letter

With nearly 10 million baby boomers at risk for developing Alzheimer’s disease, researchers are taking a closer look at a condition known as mild cognitive impairment. This is a state between the normal forgetfulness that comes with aging and the more pronounced thinking deficits of dementia. Mild cognitive impairment often progresses to Alzheimer’s disease, but some people remain stable and others recover. New technology is improving the ability to determine who might fall into each category, reports the April 2008 issue of the Harvard Mental Health Letter. These developments are promising because they are occurring just as the first disease-modifying drugs for Alzheimer’s have reached late-stage clinical testing.

One technology, fluorodeoxyglucose positron emission tomography (FDG-PET), measures blood glucose metabolism in the cerebral cortex. Diminished glucose uptake suggests that neurons are not as active. Clinicians can also measure brain volume changes with volumetric MRI to detect shrinkage, which is typical in Alzheimer’s. These techniques are likely to prove most useful when combined with detection of newly discovered proteins believed to be the first signs of Alzheimer’s.

If one of these technologies—or a combination—can reliably predict which people with cognitive impairment are likely to progress to Alzheimer’s, scientists might be able to determine who should get the disease-modifying medications now in development. And they might be able to predict which healthy people are most likely to get mild cognitive impairment, and try to prevent it.

The technologies and medications needed to predict and prevent mild cognitive impairment and Alzheimer’s are still in the early stages of development, but the Harvard Mental Health Letter says that this research will almost certainly lead to better treatments.

Hormone therapy for prostate cancer

Caution advised when using hormone therapy for prostate cancer, reports the Harvard Heart Letter

In men with localized but aggressive prostate cancer, the combination of testosterone-lowering therapy and radiation improves survival substantially more than radiation therapy alone. But testosterone-lowering therapy isn’t so hot for the heart, reports the April issue of the Harvard Heart Letter. Low testosterone can increase harmful LDL cholesterol, blood sugar, blood pressure, and weight. It can also make arteries stiffer, promote formation of artery-clogging plaque, and allow blood clots to form more readily.

Preliminary results show that testosterone-lowering therapy is associated with more diabetes, more heart disease, and earlier heart attacks. However, this hormone therapy does have a significant benefit in curing prostate cancer. For instance, one study of patients with localized but unfavorable prostate cancer found that about 90% of otherwise healthy men who underwent radiation and hormone therapy were still alive after eight years, compared with about 65% of those who had only radiation therapy. The reverse was true among those with moderate or severe health problems in addition to their prostate cancer: only about 25% of those who underwent the combination were still alive, compared with 55% of those who had radiation alone.

These findings don’t mean hormone therapy should be off limits. Quite the contrary—suppressing testosterone is a life-prolonging addition to radiation therapy for men with locally advanced prostate cancer or cancer that has spread. The Harvard Heart Letter suggests that hormone therapy be used with caution in men who have had a heart attack or who are at high risk for cardiovascular disease.

Also in this issue:

  • Angioplasty or bypass surgery?
  • Study results on cholesterol drug Vytorin
  • Tiny arteries and chest pain
  • Vitamin D and the heart
  • Aldosterone follow-up
  • WelChol and blood sugar control
  • Ask the doctor: Warfarin and vitamin K; Different kinds of stress tests; and ADHD medications and the heart

Managing common conditions without medication

Managing seven common conditions without medication, from the Harvard Health Letter

We’ve gotten used to taking pills for everything that ails us, but medications have side effects and cost money. The April 2008 issue of the Harvard Health Letter takes a look at how to manage seven common conditions without taking medication. It takes some discipline, but in many cases, the nonpharmacological approach can do as much as pills.

Here’s a brief look at the conditions and treatments:

Arthritis: There’s a good chance that losing weight will make arthritis less painful. Combine weight loss with exercise and you may have less pain and more mobility. Even for those who don’t need to lose weight, exercise that doesn’t put “load” on the joints reduces pain.

Cholesterol: Your LDL level may drop by 5% or so if you keep foods high in saturated fat off the menu. Additional soluble fiber may reduce LDL levels as well. So can margarines fortified with sterols.

Cognitive decline: Memory training and other “brain exercises” seem to help healthy older people stay sharp. But physical exercise may benefit the brain more than mental gymnastics.

Depression: Studies have shown that regular physical activity can have a potent antidepressant effect.

Diabetes: Regular physical activity is a powerful brake on blood sugar levels as well, because exercised muscle becomes more receptive to the insulin that helps it pull sugar in from the bloodstream. Eating fewer sweets and easy-to-digest carbohydrates also helps control blood sugar levels.

High blood pressure: Losing weight, getting more exercise, and eating less sodium all lower blood pressure.

Osteoporosis: Weight-bearing exercise puts stress on bones, and bone tissue reacts by getting stronger and denser, fending off osteoporotic processes. Extra vitamin D and calcium top the list of dietary recommendations.

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